Human PBMC atlas - DC_DC2 cells

pDC3_IRF4_CXCR4

Full Name: IRF4/CXCR4+ plasmacytoid dendritic cell 3
Closest Ontology Term: plasmacytoid dendritic cellCL:0000784
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: plasmacytoid dendritic cellCL:0000784
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: Cluster with canonical pDC3 markers and +IRF4/CXCR4
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: IRF4, CXCR4, SEMA7A, GPR183, SOX4, RGS1, DSTN, ZFP36
Canonical Marker Genes: IL3RA, TCF4, IRF7, IRF8, JCHAIN, LILRA4
Rationale: Cluster with canonical pDC3 markers and +IRF4/CXCR4
Rationale DOI: https://doi.org/10.1038/s41598-025-87344-6

Set of Labels Description: Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.
Annotation Method: manual