• v5 Single cell atlas of the human peripheral immune system
• Human PBMC atlas - T CD8 effector and nonnaive cells and innate lymphoid cells including NK cells

T CD8 CTL activ NR4A2

Full Name

NR4A2+ activated CD8-positive, alpha-beta cytotoxic T cell

Closest Ontology Term

CD8-positive, alpha-beta cytotoxic T cellCL:0000794

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

unknown

Category

Class of which the cell type is a subclass.

CD8-positive, alpha-beta cytotoxic T cellCL:0000794

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

Cluster with canonical cytotoxic markers (GZMA & GZMK) in addition to NR4A2 marker of activation

Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

NR4A2

Canonical Marker Genes

CD8, GZMA, GMZH

Rationale

Cluster with canonical cytotoxic markers (GZMA & GZMK) in addition to NR4A2 marker of activation

Rationale DOI

https://doi.org/10.1016/j.coi.2023.102285

Inherited from Level_4

Set of Labels Description

Clustering was Leiden based before manual annotation and consensus agreement by multiple authors.

Annotation Method

manual