Colonocyte Progenitors
Full Name
- colonocyte progenitor cell
Synonyms
Terms that have the same, or nearly the same, meaning as the selected cell type.- absorptive progenitor, colonocyte early progenitor
Category
Class of which the cell type is a subclass.- colonocyteCL:1000347
Ontology Assessment
Disagreements with any aspect of the Cell Ontology.- No specific CL term for colonocyte progenitors - we separate these from early colonocytes to provide more resolution on epithelial subtypes
Marker Gene Evidence
Gene markers used by researcher to assign this cell annotation.- NOTCH1, EDN1
Rationale
- Absorptive colonic progenitors, NOTCH1 and EDN1 with some residual cycling, committed towards the colonocyte lineage but not yet showing surface maturation like AQP8. There isn't a colonocyte progenitor term so these map to early colonocyte.
Inherited from hgca_celltype_v1
- Set of Labels Description
- Cell annotations based on two rounds of subclustering with scVI integration, sample_id as batch key. Cell annotations were refined by expert feedback based on "prelim annotation" on CAP. Prelim annotation is renamed "hgca_celltype_v0" here and the feedback on the "prelim annotation" is available by selecting a previous version of the Integrated Human Gut Atlas on CAP.
- Annotation Method
- both
- Algorithm Name
- scIB
- Algorithm Version
- 1.2.1
- Algorithm URL
- https://github.com/theislab/scib
