Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution (Murrow et al. 2022)

Lymphocyte

Ontology Term: lymphocyteCL:0000542
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: lymphoid cells
Category Class of which the cell type is a subclass.: mononuclear leukocyteCL:0000842
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CD69, CD7, CD79A, CD8A, JCHAIN, MS4A1
Canonical Marker Genes: CD69, CD7, CD79A, CD8A, JCHAIN, MS4A1
Rationale: This gene expression list spans the adaptive immune spectrum, incorporating core T-cell effector markers (CD8A, CD7, CD69), B-cell lineage markers (MS4A1, CD79A), and plasma cell secretion machinery (IGJ). This combination defines the broad Lymphocyte compartment within the mammary microenvironment.

Set of Labels Description: Cell type annotation based on clustering and marker analysis.
Annotation Method: manual