snRNA-seq of human of the human retinal pigment epithelium and the choroid - Melanocytes

Melanocytes PTPN1+

Ontology Term: melanocyteCL:0000148
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: melanophore
Category Class of which the cell type is a subclass.: pigment cellCL:0000147
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: TEX41, PTPN1
Canonical Marker Genes: TYR, TEX41, PAX3
Negative Marker Genes Genes expected to be absent, or expressed at a notably low level, in these cells, and whose absence supports the assignment of this cell annotation.: —
Rationale: This melanocyte PTPN1+ sub-class was annotatedy by markers TEX41, PTPN1

Set of Labels Description: This dataset provides high-resolution annotations and sub-clustering of Schwann cells from the human retinal pigment epithelium (RPE)/choroid complex—a tissue essential for the survival and function of the neural retina. By analyzing 61,751 nuclei across 53 donors, we resolved three choroidal melanocyte types/states.
Annotation Method: manual