Myeloid and pDC cells were identified via RCAv2. Integration and sub-clustering of all myeloid and pDC cells were performed, and these clusters were manually annotated based on expression of FCGR3A (CD16) and other marker genes. This annotation includes clusters that may contain intermediate monocytes.
Inherited from author_cell_type
Set of Labels Description
These author cell type labels were assigned largely at the per-cluster level. We identified broad cell types using RCAv2-based clustering (B, CD34+ haematopoietic stem and progenitor cell (HSPC), myeloid, natural killer (NK), plasma cell, plasmacytoid dendritic cell (pDC), platelet, and T). We then performed cell population-specific (B; myeloid + pDC; CD4+ T and dnT; non-CD4+ T and NK and ILC) integration (Seurat RPCA) and sub-clustering (Louvain clustering), and annotated clusters based on their marker genes.
