Cell Annotation
Platform

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snRNA-seq of human optic nerve and optic nerve head - all cells

Main

Cell Metadata

Ontology Term: oligodendrocyte precursor cellCL:0002453
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: OPC RNF220+, oligodendrocyte precursor cell RNF220+
Category Class of which the cell type is a subclass.: progenitor cellCL:0011026
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: CSMD1, TNR, BCAS1, RNF220
Canonical Marker Genes: TNR, BCAS1
Rationale: An oligodendrocyte precursor cell sub class that expresses CSMD1, TNR, BCAS1, and RNF220

Set of Labels Description: We used scVI for data integration and then manually annotated each cell cluster based on marker gene expression
Annotation Method: both
Algorithm Name: scVI
Algorithm Version: scvi-tools 1.3.0
Algorithm URL: https://github.com/scverse/scvi-tools