Human lymph nodes with partial T and B cell depletion

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Cell Metadata

Proliferating_cells

Ontology Term: mature natural killer cellCL:0000824
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: natural killer cellCL:0000623
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MKI67, TOP2A, H2AFZ, TUBA1B, GNLY, KLRB1
Canonical Marker Genes: NCAM1, FCGR3A, EOMES
Rationale: This cluster had the highest expression of MKI67 but most closely mapped to the natural killer clusters, so likely to be a subset of these cells, including expression of granulysin (GNLY) and KLRB1

Set of Labels Description: Cell annotations were based on the finest possible label that could describe the 16 clusters found following integration and clustering.
Annotation Method: manual

Ontology Term: mature natural killer cellCL:0000824
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: unknown
Category Class of which the cell type is a subclass.: natural killer cellCL:0000623
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: —
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MKI67, TOP2A, H2AFZ, TUBA1B, GNLY, KLRB1
Canonical Marker Genes: NCAM1, FCGR3A, EOMES
Rationale: This cluster had the highest expression of MKI67 but most closely mapped to the natural killer clusters, so likely to be a subset of these cells, including expression of granulysin (GNLY) and KLRB1

Set of Labels Description: Cell annotations were based on the finest possible label that could describe the 16 clusters found following integration and clustering.
Annotation Method: manual