Cell Annotation
Platform

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The Human Neural Organoid Atlas

Main

Cell Metadata

Ontology Term: neuronCL:0000540
Synonyms Terms that have the same, or nearly the same, meaning as the selected cell type.: nerve cell
Category Class of which the cell type is a subclass.: neural cellCL:0002319
Ontology Assessment Disagreements with any aspect of the Cell Ontology.: No specific term available for non-telencephalic neurons, (only more specific ones like mid-/hindbrain). Had to pick the generic neuron term.
Marker Gene Evidence Gene markers used by researcher to assign this cell annotation.: MAP2, MAPT, DCX, LHX1, LHX9, LHX5, EN1
Canonical Marker Genes: MAP2, MAPT, DCX, LHX1, LHX9, LHX5, EN1
Rationale: Cells expressing canonical non-telencephalic neuron markers in organoids. Expression of MAP2, MAPT, DCX + any of the other genes is sufficient to classify a cell as of this type.

Set of Labels Description: Finer curated cell type annotation of the integrated HNOCA.
Annotation Method: both
Algorithm Name: snapseed
Algorithm Version: 0.1.0
Algorithm URL: https://github.com/devsystemslab/snapseed