The Human Neural Organoid Atlas
Summary
The HNOCA includes data from 36 neural organoid datasets and includes harmonised cell type annotations, as well as curated biological, and technical metadata. The datasets in the HNCOA were integrated using scPoli. The HNOCA can be used as a reference to map new datasets onto using scArches, allowing the transfer of the harmonized cell-type labels to any new dataset.
Metadata
- Dataset Type
- Integrated. The file includes an integrated collection of datasets.
- Total Cells
- 1,767,674
- assay
- 10x 3' v3 (718,277 cells)10x 3' v2 (672,069 cells)Drop-seq (228,783 cells)10x multiome (109,255 cells)BD Rhapsody Whole Transcriptome Analysis (30,511 cells)SPLiT-seq (6,381 cells)Quartz-seq (1,441 cells)Smart-seq2 (957 cells)
- tissue
- telencephalon (802,509 cells)cerebral cortex (353,984 cells)brain (287,461 cells)midbrain tegmentum (156,397 cells)midbrain tectum (59,980 cells)arcuate nucleus of hypothalamus (26,693 cells)ventral part of telencephalon (23,517 cells)hindbrain (16,703 cells)choroid plexus (15,577 cells)cerebellum (14,285 cells)dorsal plus ventral thalamus (10,568 cells)
- organism
- Homo sapiens
- disease
- normal
Cell Labels
518,082
257,745
225,272
224,111
112,006
90,701
79,506
77,315
49,270
48,956
15,433
9,718
8,325
2,451
2,187
335,549
298,558
112,685
88,762
85,869
66,990
60,046
35,679
32,920
26,406
12,071
10,227
9,905
8,952
8,214
5,880
5,689
4,587
2,984
2,372
1,886
1,459
1,309
1,282
1,238
1,209