Lymphoid cells from human liver dataset

Summary

Cells annotated as Lymphoid cells (105,790) in larger dataset were isolated and reclustered using Total VI. Corresponding to Figure S5E in publication.

Metadata

Dataset Type

Integrated. The file includes an integrated collection of datasets.

Total Cells

105,790

organism

Homo sapiens

reported_diseases

[metastatic malignant neoplasm,colorectal cancer] (48,803 cells)[chronic kidney disease,spinal stenosis,thyroid tumor,type 2 diabetes mellitus,bursitis,cholecystolithiasis,prostatitis,cataract] (13,885 cells)[morbid obesity,hypothyroidism] (9,228 cells)[cholecystolithiasis,obesity disorder,nasal cavity polyp,asthma] (7,901 cells)[endometriosis,hydrosalpinx,hepatocellular adenoma,vitamin deficiency disorder] (5,350 cells)[injury,migraine disorder,meningitis] (4,738 cells)[Parkinson disease,abdominal obesity-metabolic syndrome,type 2 diabetes mellitus,hepatocellular carcinoma,hemorrhoid,cystadenocarcinoma] (4,579 cells)[cholecystolithiasis,cataract,carpal tunnel syndrome] (4,476 cells)[hepatocellular adenoma] (2,247 cells)[acute myocardial infarction,urticaria,abscess,pulmonary arterial hypertension,hyperlipidemia,morbid obesity] (1,548 cells)[chronic kidney disease,pituitary gland adenoma,pulmonary arterial hypertension,congenital diaphragmatic hernia,type 2 diabetes mellitus,obstructive sleep apnea syndrome,hemorrhoid,ovarian cyst,cholecystolithiasis,idiopathic progressive polyneuropathy,cystic hygroma] (1,485 cells)[squamous cell carcinoma,chronic obstructive pulmonary disease,prostate cancer,colorectal cancer] (763 cells)[spinal stenosis,Hashimoto thyroiditis,insomnia,gastroesophageal reflux disease,morbid obesity,carpal tunnel syndrome] (511 cells)[obesity disorder,cholelithiasis] (147 cells)[cholecystolithiasis,obesity disorder] (63 cells)[hypertensive disorder,type 2 diabetes mellitus,obesity disorder,obstructive sleep apnea syndrome,depressive disorder,coronary artery disorder] (47 cells)[type 1 diabetes mellitus,abscess] (13 cells)[obesity disorder] (6 cells)

mapped_reference_annotation

GENCODE 19

digest

exVivo Collagenase A and DNase (105,548 cells)nuclei (242 cells)

sample

CS81 (13,885 cells)CS87 (12,487 cells)CS112 (9,228 cells)CS85 (8,096 cells)CS126 (7,682 cells)CISE07 (6,563 cells)CISE08 (6,285 cells)CISE09 (5,986 cells)CISE06 (5,641 cells)CS46 (5,350 cells)CS83 (4,476 cells)CS110 (4,170 cells)CS108 (2,979 cells)CS101 (2,247 cells)CS109 (1,600 cells)CS71 (1,548 cells)CS32 (1,408 cells)CS33 (1,271 cells)CS34 (1,007 cells)CS37 (764 cells)CS38 (721 cells)CS111 (568 cells)CS73 (511 cells)CS44 (255 cells)CS127 (219 cells)CS43 (213 cells)CS41 (156 cells)CS42 (139 cells)CS161 (110 cells)CS31 (59 cells)CS162 (37 cells)CS171 (34 cells)CS170 (29 cells)CS166 (20 cells)CS167 (17 cells)ABU8 (13 cells)CS169 (10 cells)CS164 (6 cells)

tissue_type

Liver

donor_id

H02 (28,220 cells)H16 (20,583 cells)H13 (13,885 cells)H23 (9,228 cells)H25 (7,901 cells)H07 (5,350 cells)H22 (4,738 cells)H21 (4,579 cells)H14 (4,476 cells)H18 (2,247 cells)H10 (1,548 cells)H04 (1,485 cells)H06 (763 cells)H11 (511 cells)H30 (147 cells)H38 (63 cells)H37 (47 cells)H33 (13 cells)H32 (6 cells)

disease

normal

tissue

liver

assay

10x 3' v3 (69,972 cells)10x 3' v2 (35,818 cells)

sex

female (61,308 cells)male (44,482 cells)

Cell Labels

author_cell_type (13)

105,790 cells

RM CD8+ T cells

24,402

Circulating TEM

22,154

Tissue Resident NK

11,282

Cytotoxic CD8+

10,475

Circulating NK

8,551

Naive/CM CD4+ T cells

6,489

CD4+ Th cells

6,164

Gd T cells

5,696

NKT

5,265

B cells

2,364

pDCs

1,221

Plasma cells

1,130

Treg

597