Single-nucleus RNA-seq of Asian Skeletal Muscle Reveals Ancestry-specific Regulatory Programs Across Metabolic States

muscle fiber type 1

Ontology Term

slow muscle cellCL:0000189

Synonyms

Terms that have the same, or nearly the same, meaning as the selected cell type.

type I muscle fiber, slow-twitch fiber, type 1 myonuclei

Category

Class of which the cell type is a subclass.

cell of skeletal muscleCL:0000188

Ontology Assessment

Disagreements with any aspect of the Cell Ontology.

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Marker Gene Evidence

Gene markers used by researcher to assign this cell annotation.

MYH7, MYL3, TPM3, TNNI1, TNNC1, ATP2A2, LDHB

Canonical Marker Genes

MYH7, MYL3, TPM3, TNNI1, TNNC1, ATP2A2, LDHB

Rationale

Annotated based on canonical slow/type I myofiber markers from snRNA-seq differential expression analysis. High expression of MYH7 (slow myosin heavy chain), MYL3, TPM3, TNNI1, TNNC1, ATP2A2.

Inherited from author_cell_type

Set of Labels Description

Cell annotations are based on a Level 1 annotation scheme, assigning the most appropriate broad cell type label to each of the 11 clusters identified during integration.

Annotation Method

manual